Macromolecular Crowding and Confinement: Biochemical, Biophysical, and Potential Physiological Consequences
نویسندگان
چکیده
منابع مشابه
Macromolecular crowding: biochemical, biophysical, and physiological consequences.
CONTENTS PERSPECTIVES AND OVERVIEW ........................................................................................ 28 Nomenclature ........................................................................................................... 30 THEORETICAL CONCEPTS ............................................................................................... 31 The Effect of Macromolecul...
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Although you were born and educated in the USA, you've worked in the UK for over 11 years. What are your views on the different ways science is done in the two countries? I've probably been away from the States too long to judge! One thing that does stand out, however, is the difference in postgraduate (PhD) education and training. Most students in the UK get funding for a three-year PhD after ...
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Label-free methods to obtain hydrodynamic size from diffusion measurements are desirable in environments that contain multiple macromolecular species at a high total concentration: one example is the crowded cellular environment. In complex, multi-species macromolecular environments - in this article, we feature aqueous systems involving polymers, surfactants and proteins - the link between dyn...
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Macromolecular crowding has long been known to significantly affect protein oligomerization, and yet no direct quantitative measurements appear to have been made of its effects on the binding free energy of the elemental step of adding a single subunit. Here, we report the effects of two crowding agents on the binding free energy of two subunits in the Escherichia coli polymerase III holoenzyme...
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ژورنال
عنوان ژورنال: Annual Review of Biophysics
سال: 2008
ISSN: 1936-122X,1936-1238
DOI: 10.1146/annurev.biophys.37.032807.125817